خلاصه داستان : اسکوبی دوو و گروهش بعداز یک دوره استراحت مطلق، اکنون درگیر چالش دیگری می‌شوند! آنها باید به جزیره‌ای که آلوده به زامبی های خون آشام است بروند که در آنجا با ماجراهای ترسناک و عجیب و غریبی مواجه میشوند…

Scooby-Doo and his pals win an all-expense paid vacation and embark on a trip of a lifetime to a tropical paradise. Their destination however, turns out to be Zombie Island. As soon as they arrive, they realize the place looks strangely familiar and is reminiscent of a trip they took years ago, in which they became wrapped up in a mystery involving zombies. The gang soon learns that their trip to paradise comes with a price when the zombies re-emerge and attack their hotel. Will Scooby-Doo and the Mystery Inc. gang finally solve the mystery behind Zombie Island?